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We observed that the information provided by the differentiation status adds prognostic value even when considered with intrinsic subtype and the classical clinical variables.
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They were not significant even when considered alone (Table 2).
We apply the SLGA method to solve optimization problems involving complex combinatorial and large-scale systems and illustrate numerically how it outperforms several other competing algorithms such as Differential Evolution even when considering problems with a large number of elements.
In a meta-analysis assessing recombinant human activated protein C and including the PROWESS and ADDRESS studies, the heterogeneity of the results (efficacy in the PROWESS study, failure in the ADDRESS study) was observed even when considering patients with APACHE II score ≥ 25 [25].
However, HO remains relatively rare in the civilian trauma population, even when considering patients with concomitant TBI or SCI.
Certain components, primarily mobile elements, were abundant within these plasmids: the average plasmid shared 500 contiguous bases with 58 of the other plasmids; however, median BLAST identity for this pairwise comparison was <12%, even when considering plasmids with the same β-lactamase, suggesting that both carbapenemases exist within a variety of plasmid configurations.
In a meta-analysis assessing recombinant human activated protein C and including the PROWESS and ADDRESS studies, the heterogeneity of the results (efficacy in the PROWESS study, failure in the ADDRESS study) was observed even when considering patients with APACHE II score ≥ 25 [ 25].
However, survival remained better in the operated group even when considering only patients with partial response or patients with clinical benefit (PR or SD).
This result demonstrates that with high probability the reported clustering cannot be obtained randomly even when considering randomized genomes with similar features to the original ones (global CUB and the same proteome), supporting the conjecture that the obtained S ij-value similarities correlate with the evolutionary distances and thus have biological meaning.
P(cv-a CO2 cv-a CO2er in patients wash complargerons (7.8 ± 2 vs. 5.6 ± 2 mmHg, P < 0.001), even when consinering only patients with normal Scomplications
However, even when considering only samples with an ODP > 50%, the use of confirmatory tests proved to be essential to minimize the number of false positive reactions.
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