We employ here an additive Gaussian noise observation model even though the methodology proposed in the paper is entirely general and could be applied in principle to any observation model satisfying constraints (3) and (4).
Even though the methodology adopted by Gumpel has several strengths, it, too, is not free of limitations to apply in Sri Lankan context.
Moreover, even though the methodology is mathematically intensive, the availability of the public domain software, BayesX, and relevant literature provides opportunities for non-mathematicians or non-programmers to utilize these methods.
Likewise, even though the methodology they utilized only considers samples with the same pathologic diagnosis, it is likely that there is still an important amount of heterogeneity in their samples due to inter-individual differences.
Even though the above methodologies exhibit a good agreement on the predictions, it was found that special attention must be paid to the type of backing cavity configuration (isolated or non-isolated) to yield correct results.
When screening for sickle cell anemia became an important addition to screening panels, the singular condition of SS disease was usually counted even though the testing methodologies used could detect many different clinically significant hemoglobinopathies.
Even though the new methodology seems like it would ultimately produce students who could become better scientists, it's hard to accept such a sweeping change without some anxiety.
Gastric mucosal PCO2 tonometry has evolved as a useful adjunctive monitoring technique that is physiologically sound, simple and noninvasive, even though the precise methodology and interpretation of the results continue to be debated [ 1].
Even though the retrospective methodology would have left room for error when comparing perioperative findings and MRI, we consider our finding of a poor association between > 1-year-old MRI results and surgical findings to be clinically significant.
Limitations of this analysis include the following: meta-analyses could not be performed on a number of the endpoints due to a lack of multiple RCTs examining that endpoint and even though the search methodology was comprehensive, we were not 100% confident that all trials were identified.
