Fare sales are even proliferating in the most lucrative segment of the airline market, international premium travel, where the walkup round-trip fare for a business-class seat between New York and London has been in the $9,000 range.
Nevertheless, cellular factors can in part compensate for loss of E1 and E1-deleted Ad vectors can thus be transcribed and even proliferate in certain cell types [25], [26].
Exogenous cancer cells are known to chemotact towards, infiltrate and even proliferate within tumour masses [11], thus it is possible that the strong luminescence signal detected in the ovarian carcinoma-bearing mice is not due to the increased ATP concentration in the tumour microenvironment, but rather to the increased local density of HEK293-pmeLUC cells.
Diabetic ADSCs even proliferate at the same rate as those from normal wound healing [ 13].
This renders them more resistant and with improved ability to survive and even proliferate, promoting tumour development [ 15].
4– 6 Although hypoxia is toxic to cancer or normal cells, cancer cells undergo genetic and adaptive changes that allow them to survive and even proliferate in hypoxic conditions.
By mainly relying on anaerobic metabolism, malignant cells can not only survive but even proliferate in a hypoxic environment, so that tumor growth can exceed angiogenesis [ 13].
Although hypoxia is toxic to both cancer cells and normal cells, cancer cells undergo genetic and adaptive changes that allow them to survive and even proliferate in a hypoxic environment (Harris, 2002).
Even proliferating reactive astrocytes after CNS trauma give rise only to other astrocytes and do not spontaneously exhibit multipotent neurogenic potential unless they are reprogrammed genetically or by exposure to high doses of specific growth factors in vitro [ 29, 30].
By contrast, keritinocytes in a tensed cell sheet suspended over the ECM-devoid region, where cells are held together by actomyosin bundles interconnected through E-cadherin-mediated cell-cell junctions, are viable for > 40 h and even proliferate.
