Sentence examples for even more malignant from inspiring English sources
The most satanic presence on the dark side, even more malignant than Alexander Hamilton, was John Marshall.
Should an additional mutation or gene activation occur that suppresses this cell death, the N/Src cells may become even more malignant.
On the other hand MCF7-HPSE1 cells treated with trastuzumab increased the amounts of HPSE1, Syn-1 and HER2 after trastuzumab treatment, which could render MCF7-HPSE1 even more malignant.
Moreover and more importantly, death receptors such as CD95/Fas, TRAIL-R1/-R2 and TNF-R1 exhibit marked non-apoptotic functions after ligand binding leading to strong proinflammatory responses, which contribute to survival, proliferation, migration and invasion, causing an even more pronounced malignant phenotype.
Even more remarkably, malignant cells have evolved a variety of complex mechanisms capable of circumventing the tumor suppressing activities of TGF-β, and in doing so, typically convert the functions of TGF-β to that of a tumor promoter, particularly the induction of carcinoma epithelial mesenchymal transition, invasion, and dissemination to distant organ sites (15 18).
Thus, maintenance of telomere integrity seems even more critical for malignant than for normal cells.
Moreover, real time PCR showed a significant reduction in PRLR expression both in benign neoplastic lesions and even more marked in malignant lesions.
Most meningiomas have a benign biology and are evaluated as G1; however, some have a tendency to recur or even transform into more malignant forms.
Meningiomas are mostly benign brain tumors; however, they have a tendency to recur or even sometimes transform into more malignant tumors atypical or anaplastic with brain invasion.
It has even been suggested that the more malignant clones harbouring genetic defects such as mutations in p53 might be selected by hypoxia for the survival (Royds et al, 1998).
In our study the perceived suspiciousness of the normal cases increased even more than that of the malignant cases.
