Sentence examples for evasion from cell from inspiring English sources

The functional significance of hypoxia‐induced MIF expression is revealed by findings demonstrating that HIF‐1α dependent MIF expression is necessary for hypoxia‐induced evasion from cell senescence and that MIF is necessary for HIF‐1α stabilization induced by hypoxia and prolyl hydroxylase (PHD) inhibitors.

Moreover, genes encoding proteins involved in the positive regulation of apoptosis were heavily down regulated while those involved in the inhibition of apoptosis were strongly upregulated, indicative of evasion from cell death.

These processes have been summarized as 'hallmarks of cancer' by Hanahan and Weinberg in the years 2000 and 2011, respectively, and among those, evasion from cell death is still regarded as an essential mechanism required for malignant transformation and tumor maintenance.

Here, we provide evidence that a single point mutation in the hexon capsomere designed to enable defined chemical capsid modifications may permit both detargeting from and targeting to hepatocytes with evasion from Kupffer cell scavenging.

Historically, the experimental approach to answering these questions has been reductionist: mimic metastasis component steps (eg proliferation, adhesion, invasion, angiogenesis, evasion from immune cell killing, etc) in vitro, and study the gene(s) and protein(s) responsible for controlling each step.

K3 is involved in evasion from CD8+ T cell immunity.

Some of those proteins were suggested as responsible for the evasion from natural killer cell-mediated immune surveillance through their interaction with inhibitory natural killer cell receptors [ 49, 50].

Garg, A. D. et al. ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death.

More interestingly, the activation of β-catenin has also been involved in T reg cell exhaust or tumor cell evasion from immune surveillance by targeting PD1 and PDL1, respectively (Spranger et al., 2015; Yang et al., 2017).

In AGS this may be a mechanism of cancer cell evasion from tumor immunosurveillance as has been demonstrated in numerous cancer cell lines.

The advantage of blocking the PD1 is preventing the tumor cell evasion from the host immunity; in this manner regulating the T-cell activation.