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Acknowledgement of the different roles and perspective of team members is recommended in process evaluations of trials [ 16].
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Evaluations of trial management strategies are also under-represented in the review (e.g. evaluations of site-specific reports, El Khorazaty 2007; levels of contact by the co-ordinating centre, Senturia 1998; training project staff).
Most studies are economic evaluation of trials.
The second direction is the evaluation of trials that are used to solve the QoS problems separately.
Clinical relapse and severe endoscopic recurrence are the main outcomes in the evaluation of trials on prevention of recurrence.
However, the review lacks the quality evaluation of trials included in the review on Vitex Agnus castus.
Effective recruitment strategies and the anticipation of problems are key issues in the planning and evaluation of trials by investigators, Clinical Trial Units, RECs and funding agencies.
3 5 Table 1 shows previous studies' findings on inadequate reporting of specific aspects of trial interventions within a range of treatment areas; for example, an evaluation of trials complying with item 4 of the CONSORT statement.
Skills in the scientific evaluation of trials and a willingness to work closely with investigators were viewed as critical for the development of effective risk-based and context-informed monitoring plans.
Whatever the final outcome, these studies have made a major contribution to the design and evaluation of trials for DMD therapies and set important efficacy outcomes that are pivotal for subsequent DMD studies.
There is little knowledge about doctors and tutors' experiences with academic detailing, and process evaluation of trials has been called for to understand how academic detailing and external audit works [ 4, 7].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com