In our study, by using both the Phase II HapMap data and the disease variants extracted from OMIM, a gene-centric evaluation was first performed to evaluate the ability of the approaches in capturing the disease variants in Caucasian population.
The controlling cycle of the framework is the DET-enabled, human centric evaluation of products, plans and network configurations that gives rise to an emergent synthesis environment.
Like lean data and client-centric evaluation, Lean Research is about making the research process more relevant and meaningful and less burdensome and extractive for the people and communities involved.
During this discussion, I shared more information on Lean Research, as there is overlap between Lean Research and the client-centric evaluation approach, especially with regards to the principles of relevance and respect.
This is an eruption-centric evaluation of VALs.
This is an alert-centric evaluation of VALs.
For this reason, using the Top-n and Top-(n+2) cutoffs is more suitable for the ligand-centric evaluation approach.
The result is 55%percentt, higher than the result for eruption-centric evaluation but still rather low compared to what we expect of volcano observatories.
In this study, we perform a gene-centric evaluation to characterize the above approaches used in GWA studies.
Three genome-wide SNP chips (Human-1, GeneChip 500K and Hap550) were selected for evaluations, representing gene-centric, quasi-random SNPs and LD-based tagSNPs approaches, respectively.
We suggest that in such cases, an outcome-centric evaluation approach is not in itself and alone adequate.
