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For the various data included in the COGNIMUSE database, different evaluation setups were adopted.
Finally, Fig. 14 shows evaluation results using AUC (area under curve) as a metric comparing all modalities and evaluation setups (i.e., A-A, V-V, AV-AV, AVT-AVS).
Two evaluation setups are used, one relying on ICD-10 codes attached to care episodes, and the other relying on textual semantic similarity between discharge summaries belonging to care episodes.
To evaluate how different AFP methods perform on the NA and NP tasks, and how these evaluation protocols compare with CV, we compared the performance of GOstruct, binary SVMs and Guilt by Association GBAA) using the three evaluation setups (CV, NA and NP) using data from yeast and human.
We also suggest guidelines on how to make the supervised drug target interaction prediction studies more realistic in terms of such model formulations and evaluation setups that better address the inherent complexity of the prediction task in the practical applications, as well as novel benchmarking data sets that capture the continuous nature of the drug target interactions for kinase inhibitors.
Although the van Laarhoven et al. study [ 17] is used as an example, we note that similar problem formulations and evaluation setups have been used in many recent studies that have introduced new models and showed improved prediction accuracies [ 14, 24 26].
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"Evaluation setup" section outlines the simulation setup we use to evaluate RAP.
Evaluation setup.
Figure 3 Evaluation setup.
Section 5 presents the evaluation setup and experimental results.
AT co-supervised the research work and contributed in the evaluation setup and evaluation results analysis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com