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Astonishingly, given that personal budgets became mandatory in England from last April and the idea is being extended into healthcare, the department is still relying on an evaluation of their efficacy from 2007.
For instance, the toxicity of pan-BCL-2 inhibitors, such as Gossypol or Obatoclax, which inhibit BCL-2 and MCL1, prevented the evaluation of their efficacy in clinical settings [243].
Implementing treatment with aromatase inhibitors in the adjuvant setting was not possible without careful and systematic evaluation of their efficacy and toxicity in metastatic disease.
Because of the cost and toxicity of treatments, a rigorous evaluation of their efficacy is necessary, as well as evaluation of the toxicity.
In response to this thinking, many hospitals throughout the world began implementing various versions of RRT systems despite the lack of formal evaluation of their efficacy and safety.
Despite these limitations, this study embodies the direct translation of laboratory and clinical-based best practices for treating obesity through increased physical activity, nutritional education and counselling and allows for evaluation of their efficacy in a real-world setting.
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Figure 3 Schematic representation of PS-QD micelles and evaluation of their targeting efficacy.
Thus, we next investigated the immune responses induced by various vaccine regimens along with the evaluation of their protective efficacy in murine model.
Judging the effectiveness of different strategies requires both a comprehensive evaluation of their relative efficacy and monitoring for unintended consequences.
In this review, current antimitotic agents are summarized with particular emphasis on the evaluation of their clinical efficacy as well as their limitations.
In the current study, hypotonic (154 mosmol 1-1), isotonic (308 mosmol 1-1) and hypertonic (616 mosmol 1-1) sofutions of CDDP were prepared for an evaluation of their therapeutic efficacy in an experimental system.
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