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An evaluation of the trials is due in 2018.
For the evaluation of the trials in this review simplified version of the guidelines were developed containing only the recommendations which were deemed essential and presented in an unambiguous way which allows for clear judgment of whether the trial follows the guidelines on each point.
To facilitate a comparative costing and to enhance standardisation across our trials, the UK partner institution appointed an economics team in 2009 with overall responsibility for the evaluation of the trials.
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An independent evaluation of the trial is due next year.
Nicholas Bequelin, a researcher at Human Rights Watch, agreed with Ms. Cuomao's evaluation of the trial, noting that the 10-page verdict released Thursday night came several hours after the end of the trial, strongly suggesting that the decision was preordained.
In such trials, additional phantom measurements are commonly performed to check whether calibration differences across the different involved scanners remain within tight limits so that SUVs derived at different sites are consistent and can be pooled during evaluation of the trial data [8, 9].
Controlled-Trials.com ISRCTN64783481 A common problem in longer-term clinical trials comparing chronic treatments is that patients may start using additional active therapies during the course of the trial, which may confound the evaluation of the trial's target treatments [1], [2].
We will also undertake a full economic evaluation of the trial.
HL was involved in the design, implementation, coordination and evaluation of the trial and in the drafting of the manuscript.
The evaluation of the trial showed the median OS of 13.2 months (95% CI, 12.0 15.0) for vemurafenib arm and 9.6 months (95% CI, 7.9 11.8) for dacarbazine [ 39].
No cardiac toxicity or valvular abnormalities were described during the evaluation of the trial as it was suggested by the preclinical studies in dogs [ 20].
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