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However, the design and evaluation of such studies can be greatly improved (Altman and Lyman, 1998).
Careful development and rigorous evaluation of such studies will enable the mechanisms proposed here to be validated, refuted, extended or refined.
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This is supported by the recent statement that also broader evaluations of such studies are scarce in the literature [ 29].
But many of the existing studies are not sufficiently comprehensible for a complete external evaluation of the quality and usefulness of such studies.
The quality of such studies is assessed by health economic evaluation (HEE) quality appraisal instruments.
A comparative evaluation of such different large scale control studies conducted in India will provide newer insights to formulate better ways to meet the future challenges for cervical cancer prevention in India.
A further prospective randomised clinical study based on an evaluation of such biological markers, as the NCIC BR.19 study on adjuvant Gefitinib therapy (National Cancer Institute Central IRB protocol, 2002), should be performed.
As an option to reckless disposal, such effluents are often fermented and used as biofertilizers for nutrient-poor soils, but the potential of cottonseed oil-mill effluent (COME) and agronomic evaluation of such potential has yet been studied.
A detailed mapping of V1-V3 sites under positive selection associated with increased viral entry efficiency will lay the foundations for the development and evaluation of such novel drugs, and our study has shown the potential power of phylodynamics and high-resolution phylogeny for accomplishing this important task.
Evaluation of such a strategy will require randomised studies.
This study presents the evaluation of such a model using a combined experimental numerical approach.
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