This current review was designed to provide readers with a clear and fair evaluation of the rationale for using corticosteroids and with evidence-based decision tree for whom to treat, when, and how.
Men in this study were discerning in their evaluation of CAM information, offered rationales for their choices and often adopted a 'consumerist' approach to CAM treatment options.
An external evaluation of the current performance, rationale and funding of the six performing groups, commissioned by the Director of Audio and Music on behalf of the BBC and prepared by John Myerscough.
In their evaluation of scientific and policy rationale behind climate change-related capacity building efforts in developing countries, Glantz (2003) and Glantz and Adeel (2000) maintain that adaptation to climate change-influenced hazards, such as floods, droughts, and heat waves, is perhaps the most important mechanism developing societies need to effectively respond to climatic changes.
This hypothesis provides a framework for the design and evaluation of chemoprevention trials, including the rationale for the selection of agents that are likely to inhibit biological processes and the development of intermediate markers associated with carcinogenesis.
Although polymorphisms were not directly evaluated by Innocenti and colleagues, their clinical report suggested flavopiridol∶metabolite ratio as a possible predictor of diarrhea with flavopiridol treatment and provided a rationale for evaluation of a genetic link with UGT isoforms [31].
These studies provided the rationale for evaluation of bortezomib as a modifier of cell-cell adhesion and cellular packing density in solid tumours.
Our results thus provide a rationale for evaluation of combination therapy with ALK and MEK inhibitors in EML4 ALK-positive NSCLC patiEML4 ALK-positive iNSCLCtors alone show little effect.
These data provide the preclinical rationale for clinical evaluation of GRN163L in myeloma and in combination with 17AAG.
The results provide a strong rationale for clinical evaluation of dual BET/JAK inhibition in MPNs.
GRN163L is the first telomerase inhibitor validated for clinical study, and these data provide preclinical rationale for clinical evaluation of GRN163L in myeloma.
