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Interestingly, this adverse effect was mainly limited to patients with KRAS wild-type tumors [38] In conclusion, we document that concomitant detection of KRAS, BRAF and PIK3CA mutations and evaluation of loss of PTEN expression in mCRC patients has remarkable clinical implications by increasing the ability to predict the outcome to EGFR-targeted therapies.
According to traditional definition, architectural integrity is disrupted during pathogenesis of epithelial tumors and pathological assessment is based predominantly on microscopic evaluation of (loss of) epithelial cell features [ 11, 29].
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Our results confirm that an accurate evaluation of losses using an ACPF does modify the optimal plan and hence it is important to include an ACPF when performing Transmission Expansion Planning TEPP).
Considering the new evaluation format of loss function with intuitionistic fuzzy numbers (IFNs), we propose a naive model of intuitionistic fuzzy decision-theoretic rough sets (IFDTRSs) and elaborate its relevant properties in advance.
The fittings of experimental results to the equation gave us the direct evaluation of spurt loss volume, initial rate of fluid volume loss (flux), filter blocking and cake erosion.
Evaluation of decoding loss for three transmitters over a Rayleigh channel is given in Section 6.
The evaluation of the loss of consciousness was made by trained emergency ambulance teams, specialists in this type of situation.
This paper presents an analytical study on evaluation of support loss in micromechanical resonators undergoing in-plane flexural vibrations.
Audiometry is the gold standard for evaluation of hearing loss, but large-scale use of the procedure involves operational difficulties.
Damage parameter D is based on the evaluation of the loss of material bending stiffness and evolution of damage parameter is given versus number of impacts.
The final results provide a database for sketching a predictive rule to be used for a direct evaluation of the loss of stiffness of the joint.
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