Sentence examples for evaluation of combination from inspiring English sources
We postulated that a murine model could be used for pre-clinical stages of drug development, especially in dose response studies and evaluation of combination therapies.
It was agreed that the use of hyperimmunes in clinical trials must be standardised; clinical trials must be large enough to have sufficient power to demonstrate efficacy with clear-cut end-points, and means need to be developed, in conjunction with regulatory agencies, for the feasible evaluation of combination products.
Data suggest that continued evaluation of combination antiangiogenesis therapies may be clinically useful.
Thus the results of our investigations clearly hold promise for the evaluation of combination treatment in the form of PLGA nanoparticles in vivo.
Following therapy with BCNU plus O6-benzylguanine at 0.38 LD10, tumor regressions were seen in eight of 10 D341 Med and in all 10 D-456 MG xenografts.We recommend comprehensive clinical toxicologic evaluation of combination therapy with O6-benzylguanine plus BCNU, which would allow subsequent design of phase I clinical trials.
Reflecting this concern, the FDA in its guidance for industry for the evaluation of combination vaccines emphasizes the importance of non-inferiority tests to show that the immune response to each component of a vaccine is not less than the response to the same component in a single component vaccine[28], [29].
