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This paper presents the design, development and performance evaluation of a compound parabolic concentrator for medium temperature application.
The evaluation of a compound is associated with a certain cost while the identification of an active compound represents a gain.
In addition to providing proof of principle at an early stage of the clinical evaluation of a compound, knowledge of the time course and dose dependency of pharmacodynamic effects can help to optimise scheduling.
Evaluation of a compound's potential as a transmission control tool should involve characterization of the molecular events surrounding vector exposure.
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In vivo evaluation of a hit compound (14a) was performed in a HER2 amplified BrCa xenograft model (HCC1954) and efficacy was determined using Western blot based phosphokinase assays and immunohistochemistry.
The evaluation of a model compound with an enzyme of the same molecular weight as POP, the penicillin acylase, presented no enzymatic cleavage when Tentagel S was used, while partial cleavage was observed using PEGA1900.
In the area of RT testing, evaluation of a single compound requires hundreds of animals.
In this paper, we present the pharmacological evaluation of a five-compound series of (4R -alkyl Glu analogs (1b–e,g) which may be envisaged as conformationally released designs of ATPA and 4R -alkylenes 2a–h.
Evaluation of a promising new compound for RA in the common marmoset will always require establishing crossreactivity of this new compound for targets in the common marmoset.
Here we describe the design, synthesis, and pharmacological evaluation of a set of compounds structurally related to the high affinity serotonin 5-HT7 receptor agonist N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide N- 4-cyanophenylmethyl -4- 2-diphenyl -1-piperazinehexanamide 6
Here, we report the synthesis and biochemical evaluation of a number of compounds as potent inhibitors of cytochrome P450 enzymes, such as aromatase (AR), but not cholesterol side chain cleavage (CSCC).
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