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Since the start of the NELSON study, numerous studies on CT nodule evaluation in the trial have been published.
Participants could not be current ACT or ICM clients because these services were provided to the intervention group and their effectiveness was under evaluation in the trial.
The primary outcome measure for the economic evaluation in the trial will be the quality adjusted life year (QALY) as assessed by the EQ-5D-5 L [ 31].
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The time schedule of these evaluations in the trial is shown in Table 2.
The safety evaluation in this trial showed that epoetin alfa increases the incidence of clinically relevant thrombotic events (16.5 vs. 11.5, p = 0.008).
Results of the economic evaluation in this trial were therefore of limited significance.
Completion of this phase resulted in the final website ready for evaluation in the RAISIN trial [ 23].
Thalanany MM – 1) made substantial contributions to conception and design of the economic evaluation in the CESAR trial 2) design of all economic questionnaires, 3) transport data collection 4) design and analysis of the cost of visiting study, 5) was involved in drafting the manuscript and 6) has given the final approval of the version to be published.
As a result of this publication of the methods for the economic evaluation in the CESAR trial prior to publication of the results, we shall be open to scrutiny for any changes to protocol in our reported data collection and analysis.
These new strategies would need evaluation in the future trials.
This economic evaluation was included in the trial protocol.
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