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After screening of abstracts or titles, 925 irrelevant studies were excluded, leaving 53 eligible studies for the full-text review and evaluation eligibility.
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During the study period, 591 patents underwent evaluation for eligibility (Figure 1).
However, it remains unknown to what extent the results apply to the average clinical setting because the percentage of patients approached for initial evaluation of eligibility and those who participate in the trials is not routinely reported (Toerien et al. [2009]; Schulz et al. [2010]).
During the study period, 591 patents underwent evaluation for eligibility.
Two sources of information of donor evaluation for eligibility were included in the study.
Full texts of the screened studies were obtained for further evaluation for eligibility.
Cases were patients with newly diagnosed primary osteosarcoma admitted for evaluation of eligibility for limb salvage surgery.
Patients were referred to the ART programme for evaluation for eligibility for antiretroviral treatment under national guidelines.
Patients suspected of malaria by healthcare professionals at the health facilities were sent to research assistants for evaluation of eligibility and possible recruitment into the study.
One author scanned titles and abstracts and retrieved the full text of potentially relevant articles for evaluation of eligibility, scanned the reference lists, and contacted authors.
The agreement in article evaluation for eligibility and in extracting the data was both relatively high (kappa = 0.74 (0.70-0.78) and kappa = 0.86 (0.82-0.90)), respectively.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com