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In addition to clinicopathologic evaluation, concordance was assessed for diagnosis and histologic findings.
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Phase 2 videos were reviewed by the colposcopist at each study site, allowing the evaluation of concordance between EIS measurements and biopsy sites.
This definition was prospectively defined for this biomarker study before the start of the statistical evaluation in concordance with previous studies [ 12, 17].
The chi square test was used for the evaluation of concordance in the early breast cancer setting while in the verified metastasis group, where a lower number of cases was studied, we performed the Fischer's exact test.
Twenty-six of the 27 diluted specimens examined with both microscopes resulted in concordant evaluations (96.3% concordance).
Fourteen of the 18 direct specimens examined with the two microscopes resulted in concordant evaluations (77.7% concordance).
M. tuberculosis bacilli could be clearly resolved at 400× magnification, as seen in Figure 2. Seventeen of the 19 decontaminated specimens examined with the two microscopes resulted in concordant evaluations (89.4% concordance).
For the RV subjective function evaluation, we observed concordance rates of 93.8%, 100 % and 100 at each of the steps, respectively.
The PE evaluation displayed improved concordance between the students and echocardiographers when the first and second evaluations were compared (94% vs. 100%), with a drop in concordance to 84% at the third evaluation (p = 0.25).
In the light of these observations, the current study aimed at an objective evaluation of the concordance between experimental and clinical cases of systemic inflammation and benchmarked endotoxemia against sepsis of various origins at the level of metabolic response.
We chose to use distance matrices rather than gene trees for the evaluation of gene concordance, because trees are brittle: a small change in sequence can dramatically change tree probabilities or the topology of the likeliest tree.
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