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Prospective multicentric translational studies embedding these newer modalities are needed to confirm the ability of these techniques to do better than bone scintigraphy and CT in terms of disease detection, demonstration of recurrence and to provide an earlier, more refined approach of response evaluation and defining the optimal timing to switch treatment or type of treatment.
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Also, it is intended to develop methodology for process evaluation and define areas for improvement based on lean approach principles.
We have also examined the delicate issue of performance evaluation and defined the error as a function of wavelength, using a metrological procedure to infer the uncertainty of the computed error from the statistics of the measured variables.
One important point of this opinion that holds true is the necessity of standardization of the overall tissue processing steps, from the time gap from surgery to the staining, in order to homogenize the diagnostic evaluation and define a uniform diagnostic criteria.
To ensure the research instrument's reliability a group discussion, including PhD students, lecturers and a professor about the method, the data, the evaluation and especially the defining of categories, occurred.
12 The Medical Research Council (MRC) framework recommends that complex interventions be modelled before evaluation in a randomised controlled trial in order to optimise the intervention design and its evaluation by defining outcomes and ensuring feasibility.
For this study, using unmarked transcripts, the first two authors individually deconstructed each "husband" story into the following story elements: abstract, orientation, complicating action, resolution, evaluation and coda, as defined by Labov and Waletzky [ 49].
The data presented here demonstrate the importance of comprehensive expression analyses of missense and deletion mutations in the GNPTAB gene in the context with a thorough clinical evaluation and help to define genotype phenotype correlations in order to improve the predictions of the clinical course of MLII and III alpha/beta.
In the UK, there are no guidelines for using clinical and economic evaluations, and no defined limit at which the incremental costs and clinical benefits of a treatment favour its introduction into routine clinical practice.
Final steps in the process would be to a) apply the results to exposure-to-dose models, similar to the Modeling Environment for Total Risk (MENTOR) approach (Georgopoulos 2008), but simplified and standardized for product evaluations, and b) define the potential contact and exposure to compound X or final form.
The author proposes the measured item (evaluation key point) and define indicators for them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com