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Table 2 Comparisons of meta-analyses evaluating timing of RRT initiation in AKI and patients outcomes Population setting Enrolled studies Outcomes Results (benefit of early RRT) Limitations Current study Mixed patients with AKI (n = 1627) Total nine RCTs.
Meta-analysis of trials [147] looking at timing of dialysis suggests that there is a signal for improved outcomes with earlier starts; however, it is not clear what is the definition of early as there are no standard criteria for evaluating timing of dialysis [148 151].
Progression of OA is generally slower in large animals, providing scope for evaluating timing of intervention, but they require more drug and are more expensive.
A recent meta-analysis evaluating timing of referral before starting RRT, has shown that patients referred late to nephrologists have a two-fold higher risk of death compared with early referral (relative risk 1.99; 95% confidence interval (CI), 1.66 to 2.39, p < 0.001) [ 5].
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To evaluate timing perception ability and motor coordination in children with ADHD (Attention Deficit Hyperactivity Disorder) while rope jumping at different rates.
Dates of onset were used to evaluate timing of illness in relation to school closure and possible transmission within households.
We were not able to evaluate timing of past vaccinations for patients with an infrequent vaccination history.
Large randomised trials are needed to evaluate timing of cord clamping and placental transfusion for both term and preterm births [ 24].
Some studies have taken advantage of the complementary nature of LHT and DRL to interpret the behavioral effects of drugs in rats [ 34- 37] and to evaluate timing in children [ 37], as is our strategy here.
We also evaluated timing of exposure by trimester of pregnancy using a trimester × cold season interaction term, but the small sample size restricted our ability to detect an interaction effect.
To determine the optimal follow-up strategy after esophagectomy for adenocarcinoma of the esophagus or gastroesophageal junction by evaluating the timing of recurrence and the method that first detected the recurrence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com