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MP took the lead on the assay evaluation and modification, as well as in evaluating the test performance.
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A numerical analysis including a cohesive mixed-mode damage model was performed considering different mixed-mode loading conditions to evaluate the test performance.
The positive likelihood ratio (LH) was computed to further evaluate the test performance.
To our knowledge, only one other study has evaluated the test performance of the NICE traffic light system.
Thus, the purpose of this study was to evaluate the test performance of the PHQ-9 for detecting major and minor depression in elderly patients in primary care.
We defined cut-off points and established a diagnostic algorithm based on the first set of patients and controls; subsequently we evaluated the test performance in the other set of cases and controls.
We evaluated the test performance of a yes/no single item screener for depressive disorders ("Have you felt depressed or sad much of the time in the past year?") in comparison to the depressive disorder module of the Patient Health Questionnaire (PHQ-9).
We recruited consecutive participants from hospital-based and community-based screening sources; the former (deviation cohort) was used to evaluate the test performance and the latter (validation cohort) was to confirm the reproducibility and applicability of the screening strategy in the community.
However, this study was limited to evaluating the test kit's performance using a serum sample.
The statistical analysis of the results was based on evaluating the GP88 test performance for its ability to predict recurrence using Kaplan-Meier curves and the Cox proportional hazard (CPH) models for quantification of risk.
The diagnostic value of CTCs detection for the gastric cancer was calculated to evaluate the overall test performance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com