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The purpose of the study was to establish the optimal dose of capecitabine (X) to be used within a multicentre, randomised study evaluating the potential roles of oxaliplatin (O) and X in chemonaive patients (pts) with advanced oesophagogastric cancer.
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We recommended spatially mapping the relevant parties, evaluating the potential role each party might play within a coalition, disarming potential spoilers in advance, and defining a purposeful sequence for approaching the parties.
These discoveries led to the design and development of many small-molecule inhibitors of FXa, which have provided potent and selective tools for evaluating the potential role of FXa in various diseases.
However, evaluating the potential role of p38 MAP kinase signaling in mediating apoptosis or oxidant injury through modulation of the cytoskeleton is beyond the scope of the present study but warrants further investigation.
Numerous reports evaluating the potential role of breast MRI in defined patient populations have been published.
Further clinical trials are underway evaluating the potential role of personalized antiplatelet therapy [ 39].
However, our study opens the door for future trials evaluating the potential role of non-operative options for DCIS.
Ongoing clinical trials are evaluating the potential role of T-DM1 as first-line treatment of MBC and in the adjuvant and neoadjuvant settings [ 64].
There is, however, a need to undertake a systematic appraisal of the epidemiologic evidence evaluating the potential role of environmental chemicals as determinants of DNA methylation in adults.
These considerations should be weighed when evaluating the potential role of candidate genes in determining lifespan and rates of aging in mice and other mammalian species.
This scenario is appropriate for investigating the infection of R. sanguineus by Leishmania spp. and for evaluating the potential role of R. sanguineus in the transmission of canine visceral leishmaniasis (CVL).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com