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Therefore, the development of a noninvasive and high-throughput analytical method is needed for evaluating the potency and efficacy of drugs in vitro during the early stages of drug discovery.
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To evaluate the potency and duration of three subparalyzing doses of vecuronium (VEC) in isoflurane-anesthetized horses.
To design potent, safe and selective inhibitors of furin, we evaluated the potency and selectivity of the derivatized peptidic inhibitors modeled from the extended furin cleavage sequence of avian influenza A H5N1.
To evaluate the potency and selectivity of BU-32 for the three proteasome catalytic active sites, we monitored the rates of fluorogenic peptide substrate hydrolysis by the proteasome in intact cells.
High Performance Thin Layer Chromatography is one of the modern sophisticated techniques than can be used for evaluating the potency, authenticity, quality and purity of crude drugs [ 23].
These findings emphasize the critical importance of defining the activity level of participants when comparing young and old and/or evaluating the potency of an intervention in attenuating or reversing aging-associated pathologies.
Conventional bioassays thus help in evaluating the potency of the hormone, since formation of fructose and sialic acid in the accessory reproductive organs of the male is directly dependent on androgenic activity [ 24, 25].
Evaluating the potency of the many known inhibitory compounds is a tedious and time consuming task, yet it can be achieved using computing tools.
To achieve this goal, evaluating the potency of several cell types from liver tissue (primary hepatocytes and hepatocarcinoma) would be a relevant challenge in the field of liver engineering.
So we established a high throughput screen using L6 differentiated muscle cells as a model for evaluating the potency of natural product extracts in inducing glucose uptake.
Since Treg are being explored for therapeutic use, a short-term functional assay could serve as a valuable tool for evaluating the potency of Treg.
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