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As a result, it is now increasingly common in early clinical trials to see traditional clinical outcomes (evaluating the activity of the drug under evaluation in terms of tumour shrinking or disease response) used together with biological measures (evaluating molecular or cellular critical events).
Patch clamp experiments evaluating the activity of single enantiomers as AMPAr positive allosteric modulator showed that R stereoisomer is the active component.
We provide here an overview of biochemical and cell-based assays evaluating the activity of inhibitors of clinically important viruses.
The anodic peak observed in the forward scan corresponds to ethanol oxidation, which is of great significance for evaluating the activity of the catalysts [29].
Therefore, the present model can be used parallel with the known in vivo ischemia models in understanding the mechanistic insight of ischemia development and in evaluating the activity of anti-ischemic drug.
Toxicity was investigated after 48 hours of exposure by evaluating the activity of several biomarkers: erythrocytic nuclear abnormalities (ENA) and Comet Assay, to study any genotoxic effect; acetyl-cholinesterase (AChE) to investigate neurotoxicity; ethoxyresorufin-O-deethylase (EROD) to assess the presence of lipophilic toxins.
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Procedure described above was used to evaluate the activity of SP1 in preventing biofilm formation.
The polarization and power density curves were used to evaluate the activity of the materials synthesized.
The decreasing concentration of MB in the photocatalytic reaction was used to evaluate the activity of the composite.
Figure 4 illustrates the difference between the two methods used to evaluate the activity of the bladder contents plus voids.
Electromyograms were used to evaluate the activity of middle gluteal and biceps femoris muscles.
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