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We first evaluated GO classification for each miRNA-correlated gene set.
Lo-Coco et al evaluated GO as monotherapy for molecularly relapsed APL.
Motivation: Recently, a shift was made from using Gene Ontology (GO) to evaluate molecular network data to using these data to construct and evaluate GO.
n represents the number of genes which are annotated as the evaluated GO functional category in HPRD PIN.
46 Estey et al evaluated GO and all-trans retinoic acid (ATRA) in patients with previously untreated APL.
We evaluated GO classification for each miRNA-correlated gene set of more than 50 genes (Table 4).
This program was used to extract GO terms associated to each of the obtained hits and returned an evaluated GO annotation for the query sequences.
To evaluate GO information, we selected top 500 GO terms ranked by MRMR and added them iteratively from top 1 to top 500.
42 Estey et al evaluated GO with or without interleukin 11 (IL-11) compared to patients who had received idarubicin and continuous-infusion, high-dose cytarabine (IA).
The DIA analysis was used to evaluate GO terms under the 3 main GO classes, including Biological Processes (BP), Cellular Components (CC) and Molecular Function (MF), as summarized in Figure 4 and Additional File 2 (Sheets 'GOTERM BP'GOTERMERM CC' and 'GOTERM MF', respectively).
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