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Gerald Black, from Southfield, envisions a stylus or pen bearing detection technology like a fingerprint sensor, a microphone for voice recognition, a camera for facial imaging and even a cell analysis system for evaluating DNA.
"By 2020, we will be taking and evaluating DNA samples, creating in-depth blood analysis and whatever other information we can gather and use to try to be as preventive and personalized in our use of medical technology as we can be," he said.
The in vivo Comet assay is a sensitive method for evaluating DNA damage.
This method enables calculation of the starting template concentration and is therefore a frequently used analytical tool in evaluating DNA copy number, viral load, SNP detection, and allelic discrimination.
Quantification of apoptosis was performed by evaluating DNA fragmentation in ethanol-fixed cells using propidium iodide (PI, Sigma).
When evaluating DNA results, one always should consider that contamination with modern DNA is a potential explanation for the observed sequence differences.
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BrdU labeling was used to evaluate DNA synthesis.
To evaluate DNA fragmentation in spermatozoa with normal morphological appearance.
Hence, RBCs are frequently used in fish to evaluate DNA damage by the comet assay method.
This study also ascertained that the proposed biosensor can be profitable to evaluate DNA bases damage.
In addition, when cellular DNA degradation is evaluated, DNA strand repair mechanisms will reduce the level of particle ROS-induced strand breaks [42].
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