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In a recent study from Sweden, evaluating breast density quantitatively, comparing 1115 screening-detected breast cancers and 285 interval cancers in postmenopausal women, women with interval cancers had generally more aggressive tumour characteristics and worse 5 year survival, although these differences were most pronounced among women with non-dense breasts [ 40].
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The main goal was to evaluate breast density as a breast cancer risk factor by detection mode, histology and time since the original mammogram.
These results are in line with the conclusions of Mendelson et al., who evaluated breast density as a predictor of mammographic lesion detection [ 31].
UST holds promise as a robust, reliable and accurate technique to evaluate breast density without the use of ionising radiation and has additional benefits of lower cost and greater patient acceptability.
We evaluated how DOSI could be used to assess breast density while gaining new insight into the impact of chemotherapy on breast tissue.
AM evaluated breast density.
Visual inspection is generally used to assess breast density.
This work is a part of a computer aided diagnosis project aiming at evaluating breast cancer risk and its association with characteristics (density, texture, etc). of regions of interest on digitized mammograms.
To our knowledge, no previous studies have evaluated mammographic breast density in relation to biological measures of phthalate, paraben, or phenol exposures.
Several studies have evaluated predictors of breast density in women who have not been diagnosed with breast cancer.
In addition, the method used to determine MPD has previously been validated (Martin et al, 2006), including use in a study evaluating genetic associations with breast density (Douglas et al, 2008), and had multiple prospective quality measures in place to minimise intraobserver variability and other sources of bias as described in the Materials and Methods section.
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