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Six refrigerants are evaluated as low GWP replacements for R404A using different configurations, including two-stage system architectures.
Of the 7 included studies, 6 had high risk of bias with many design/reporting faults, with only one OMT study (n = 25) being evaluated as low risk of bias.
Each of these domains was evaluated as low or high risk of bias.
The overall risk of bias was evaluated as "low" for five studies and as "medium" for two studies.
NADH-tetrazolium reductase staining intensity was subjectively evaluated as low, medium and high in the different fibre types.
The attitudes towards continuous improvement in Japanese healthcare workers and the reporting of near-miss events in Taiwanese healthcare workers were evaluated as low.
The final results were evaluated as low (1 9 CFU/tube), moderate (10 50 CFU/tube) or heavy (>50 CFU/tube) faecal shedding [ 23].
Acetic acid (70%) provided lower conductivity than 0.25% formic acid and was evaluated as low ionic-strength and a CZE MS compatible sample buffer with good protein solubility.
VEGF protein expression, evaluated as low and high on the basis of median value of the series (mean 40.1, range 0 90%), significantly affected overall (P=0.0008) and disease-free survival.
According to our pre-defined methodological quality criteria, no trial could be evaluated as low risk of bias, the majority of the 73 included trials were evaluated as high risk of bias (Table 1: Reporting of five quality components in randomized clinical trials on cupping therapy).
3 4 10 12 22 23 25 44454749505456576061646667687071 64 66 67 68 70 71 Details of methodological quality of included studies according to the Newcastle-Ottawa Scale are provided in appendix 3. The data originally from two randomized trials 47 68 were evaluated as low risk of bias on all five components of the Cochrane tool.
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