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7 Evaluating a role for eculizumab in the management of aHUS requires an assessment of previous best practice.
We have therefore developed, and are currently evaluating, a role play-based measure for use with simulated patients.
In addition, substantial toxicity — particularly bone marrow and neurotoxicities — was evident with the higher-dose cisplatin treatment in both the above trials; to date, no large randomised studies evaluating a role for true high-dose chemotherapy have been performed.
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The aim of this study was to evaluate a role of fosfomycin therapy in the development of HUS in children who contracted STEC infection.
We evaluated a role for GATA and Ebox binding proteins in the direct regulation of PGC-1α promoter activity and mRNA expression.
To evaluate a role for YopJ and YopP in induction of cell death, we measured LDH release and membrane integrity via EthD-1 staining in the murine J774A.1 cell line and HMDMs following interaction with Yersinia.
Given this association of EBV and NPC, investigators have evaluated a role for immunotherapy.
Larger prospective studies will be needed to fully evaluate a role for Siglec-6 as a diagnostic marker.
Due to the limited number of samples evaluated, a role for Siglec-6 in GTN remains speculative.
The aim of this study was to evaluate a role for nm23-H1 in responsiveness to cisplatin-based chemotherapy in patients with oesophageal squamous cell carcinoma (OSCC).
Finally, we also measured pPKRThr446 and peIF2 αSer51 in the gastrocnemius muscle in order to evaluate a role of PKR-eIF2 α pathway inhibition in the muscle.
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