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The researchers evaluated trials for inclusion, extracted data and assessed study quality.
In cases of author non-response, the reviewers evaluated trials based on information available in the publication.
This review included eight trials published in peer-reviewed journals and eight evaluated trials from the grey literature.
Two reviewers searched and evaluated trials for inclusion in the analysis, and data were collated and checked by both reviewers before inclusion.
13, 35, 36 EGb 761 was well tolerated in all evaluated trials, with rates of adverse events, serious adverse events, and premature adverse event-related withdrawals not being conspicuously different between the active treatment groups and placebo.
A Cochrane review by Empson et al. [ 51] evaluated trials of heparin (N = 13) in pregnant women (N = 849) with a history of pregnancy loss and anti-phospholipid antibodies or lupus coagulant (Additional file 11).
Similar(48)
Of the 48 items included in PT tools, 16 (33.3%) evaluated trial "reporting" whereas 28 (58.3%) evaluated "conduct".
In evaluating trials of new drugs and procedures, the Food and Drug Administration does not accept such subgroup analyses, requiring a second trial for the subgroup that may benefit.
Twelve (of 40) of the fixed dose evaluating trials planned an interim analysis for dose confirmation, reflecting a degree of caution about dose.
Using weighted κ, moderate inter-reviewer agreement was achieved on evaluating trial risk of bias (Cohen κ 0.602, 95% CI 0.402 0.788), with 100% agreement following discussion [44,45].
Conflicting stereotypes and expectations about defendants and victims, and about the crime itself, influence jurors as they evaluate trial evidence.
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CEO of Professional Science Editing for Scientists @ prosciediting.com