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Each hyponatraemic patient has been also evaluated through standard clinical and laboratory tools by expert physicians, blinded to ultrasound measurements.
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In our previous study, the CANDU6 PCR was evaluated through a standard lattice analysis at mid-burnup and was found to be negative at low power.
Vascular ultrasound examination for brachial endothelial function, carotid IMT and presence of carotid plaque was evaluated through a standard B-mode ultrasound examination with the use of a 7.5 MHz linear array transducer and a high resolution ultrasound system (Agilent Sonos 5500, Philips, Andover, Massachusetts, USA) as described previously [ 18].
The accuracy of predicted secondary structures was evaluated through the following standard evaluation measures: Sensitivity = TP/ TP + FN) and PPV = TP/ TP + FP), where TP is the number of correctly predicted base pairs, FN is the number of base pairs in the reference structure that were not predicted and FP is the number of incorrectly predicted base-pairs.
Design flexibility of t-QCA then evaluated through synthesis of standard functions.
The influence of stabilizers is evaluated through Atterberg limits, standard Proctor compaction, unconfined compressive strength, splitting tensile strength, modulus of elasticity and California bearing ratio (CBR) tests.
This permits the specificity to be evaluated through the average and standard deviation of the noise amplitude (S/N), expressing relative to the internal standard signal amplitude.
In the same way, the influence of the manufacturing process is also evaluated through the comparison of a "standard" stainless steel and a stainless steel prepared by Additive Laser Manufacturing ALMM).
Validity of candidate models was also evaluated through the percent of relative standard error (RSE) of the parameters and goodness of fit plots such as visual predictive check (VPC).
Item performance was evaluated through assessment of item means and standard deviations (SD).
The networks proposed by the different teams, were evaluated through their comparison with a gold standard, a set of experimentally verified regulatory interactions in the target organisms.
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