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We also evaluated the replication of viruses by directly measuring viral E protein levels by using 2 MAbs.
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To evaluate the replication of H9N2 viruses in chickens, tissues were collected for virus titration.
To evaluate the replication of our analyses in the two independent datasets, we used the log-rank test for equality of Kaplan-Meier functions.
In this study, we have evaluated the replication and pathogenicity of APMV serotypes 2 to 9 in mice by a natural (intranasal) route of infection.
Since it is well established that the ability of a primate lentivirus to replicate in cultured PBMC is predictive of its ability to productively infect the donor monkey, we randomly selected nine RM as PBMC donors to evaluate the replication kinetics of parental SHIV-1157ipEL in vitro.
In recent years, ferrets have been used to evaluate the replication and transmission of the recovered 1918 H1N1 viruses, recent H5N1 viruses and various H5N1-H3N2 reassortants, as well as viruses of the H7 subtype [35] [39].
To evaluate the replication and transmission of avian H9N2 viruses, we first determined whether H9N2 viruses could establish significant infections in the ferret model and whether these viruses could be transmitted to direct contact ferrets.
The binding affinities of the compounds to the M2 protein of influenza virus A/chicken/Germany/27 (Weybridge strain; H7N7) were measured for the first time using an assay based on quenching of Trp-41 fluorescence by His-37 protonation, and their antiviral potencies were evaluated against the replication of influenza virus A H2N2 and H3N2 subtypes and influenza virus B in MDCK cells.
To further evaluate the intracellular replication of wild type bacteria in macrophages we employed a highly sensitive single cell analysis to evaluate the number bacteria per LCV formed after 9 hours infection in BMDM obtained from fresh or cryopreserved BM cells.
We therefore evaluated the stability of DNA replication fork in UNG−/− cells.
To assess the potential risk of infection with influenza A H9N2 viruses in mammals, we evaluated the efficiency of viral replication in primary, well-differentiated NHBE cells grown at the air/liquid interface.
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