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Few genetic association studies have evaluated the linkage between TLR9 SNPs and infectious diseases.
We then evaluated the linkage relationship between CNVs and neighboring SNPs.
We evaluated the linkage power of the pedigrees by investigating the genetic linkage between the brown phenotype and the TYRP1 gene in the complete pedigree.
We evaluated the linkage disequilibrium (LD) between the tag SNP rs4112788 and the LCE3C_ LCE3B 32-kb deletion [ 16] in all the populations analysed.
Using the LDMP, each registry evaluated the linkage on the following aspects: Linkage success: defined as the proportion of cases in the CA database that could be linked to the primary care/prescription data.
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Consequently, we designed this study to evaluate the linkage between the distribution of bGDGTs, their biological sources and inferred metabolic processes based on the distribution and abundance of bGDGTs, pertinent water chemistry, the nirS gene (possibly in Beta- and Gamma-proteobacteria) and available 16S rRNA (tag) gene pyrosequencing data from 37 Tibetan hot springs.
Genotypes for each population were also retrieved and analysed to evaluate the linkage disequilibrium between variants.
To further assess the finding from the adult case-control study that TLR1 N248S and S602I were associated with TB disease susceptibility, a separate family-based study was conducted to evaluate the linkage between these two common variants and TB disease.
To evaluate the linkage between relA and spoT and the production of ppGpp, we constructed ΔrelA, ΔrelA ΔspoT [24] and ΔrelA ΔspoT ΔlacZ::TT araC PBAD spoT mutants of Y. pestis KIM6+ strain (Fig. 1).
To evaluate the linkage effort, the participating registries provided tables generated by LDMP.
Logistic regression analysis was performed to evaluate the linkage between OCD and associated factors.
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