Sentence examples for evaluated the functional impact from inspiring English sources
We evaluated the functional impact by measuring circulating serum factor I (FI) protein levels in individuals with and without rare CFI variants.
We evaluated the functional impact of TFs during EMT by integrating ChIP-Seq data with gene expression data in A549 cells treated with TGF-beta to induce EMT.
We used the software CooVar to evaluate the functional impact of sequence variants on protein-coding genes (supplementary table S2, Supplementary Material online) (Vergara et al. 2012).
We used publicly available expression data from a study of uterine fibroids (Guo et al. 2014) to evaluate the functional impact of identified candidate loci.
Furthermore, the ability of such methods to evaluate the functional impact of individual changes makes them useful for directing mutagenesis efforts, so that mutations that are most likely to produce a phenotype can be examined first (Henikoff and Comai 2003).
Our study demonstrates that the effects of a disease-associated CD36 SNP might be tissue and transcript specific, and this should be considered when evaluating the functional impact of particular SNPs and their clinical utility as potential biomarkers of disease susceptibility.
In the absence of normality of transcript levels (evaluated by Shapiro-Wilk's test), the last two tests were taken into account for the evaluation of the functional impact of the variants.
These trailblazing publications set evolutionary biologists to work re-evaluating their interpretation of the functional impact of the plateaus in the forces of natural selection which follow their decline [ 19, 20].
