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In addition, we evaluated test performance when classifying IPA according to the predefined EORTC/MSG criteria (without ICU stay as a host factor) [ 34] and a previously published clinical algorithm [ 35], instead of our modified EORTC/MSG criteria.
The Screening for Impaired Glucose Tolerance Study evaluated test performance of random glucose and 1-h GCT and found that both tests showed reasonable discrimination for identifying dysglycemia, with estimates of AUC of 0.72 for random PG and 0.82 for 1-h GCT, although their definition of dysglycemia was slightly different (IGT, IFG ≥110 mg/dL, or diabetes) (21, 27).
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Chart review was used to evaluate test performance and the ability to detect clinical time zero, the point in time when a patient develops severe sepsis.Two physicians reviewed 100 positive cases and 75 negative cases.
In addition to its utility for evaluating test performance, LCA may also be employed as a clustering algorithm, based on the posterior probability of subject membership in each latent class.
A hospital-based deviation cohort of 3172 participants to evaluate test performance and a community-based validation cohort of 3621 to verify the findings.
Most authors evaluating test performance have reported the optimal performance of the test, with 1 or 2 musculoskeletal radiologists unblinded to the fact they were participating in a study.
In all studies that evaluated test-performance time, except one [ 21], US time was significantly shorter than CXR time (mean, <5 minutes versus 10 to 15 minutes).
As such, this provides the foundation for Phase 2b and 2c trials, that is, assessing whether the combined MRS-DTI measures are related to severity of disease and evaluating test accuracy performance in subjects with suspected disease.
Recent studies have evaluated EIA test performance among women in labor [11], [12].
To our knowledge, only one other study has evaluated the test performance of the NICE traffic light system.
We defined cut-off points and established a diagnostic algorithm based on the first set of patients and controls; subsequently we evaluated the test performance in the other set of cases and controls.
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