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The present large-scale, population-based study evaluated SAD by comparing it with WC as a measure of VAT, and we suggest that SAD is a more reliable index of VAT.
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Furthermore, we argue that the activity of evaluating a SAD is not very different from that of searching through the SAD during normal development activities, so the threat effect is reduced.
Next, we evaluated our method in SAD accuracy.
In stage 1, 95 variants in 75 genes that were previously reported as SAD-risk genes in Caucasian populations were evaluated in 1857 subjects (422 SAD patients and 1435 controls).
Specifically, individuals with SAD evaluate social situations as more threatening, and others are highly likely to evaluate the SAD sufferer negatively.
The unmixing results are evaluated by AME, SME, and SAD.
First, our proposed approach was successfully evaluated with 2 experiments involving SAD users.
We evaluated seasonal variation in amygdala activation in SAD and healthy controls (HC) using a longitudinal design targeting the asymptomatic/symptomatic phases of SAD.
Since our biochemical data indicated elevated APP β-CTF levels in ADAD compared to SAD and controls, we next evaluated the distribution of APP accumulation.
The aim of the present study was to evaluate the usefulness of SAD in predicting visceral obesity by comparing SAD to WC, BMI, and TAD.
In stage 2, a subset of promising variants found in stage 1 were further evaluated in an independent cohort of 1001 subjects (254 SAD and 747 controls).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com