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The evaluated responses were mean dissolution time (MDT), crushing strength and elastic modulus of pellets.
The evaluated responses were drug release at pH 1.2, 6.4, 6.8 and 7.4.
The evaluated responses were crushing strength or yield point, elastic modulus and mean dissolution time (MDT) of pellets.
The evaluated responses were hardness, percent cumulative drug release (% CDR) at 5th h and t90% (time required for 90% of drug release).
The evaluated responses were lag time prior to drug release at pH 6.8 (the time required for drug release up to 2%) and percent of drug release at pH 6.8 in 5 h.
The evaluated responses were the efficiency of the coating process and the agglomeration index.
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The evaluated response was the average recovery for all the analytes.
Tests for tumour markers and documentation of measurable disease by computed tomography (CT) to evaluate response were performed after every two cycles.
Currently reliable clinical or molecular markers to evaluate response are still lacking, even though metabolic response prediction has recently been evaluated as a method [ 25].
The role of platinums, topoisomerase inhibitors and temozolomide has also evaluated but responses are rarely durable.
Humoral and cellular immune responses were evaluated after each immunization.
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