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Therefore, we repeated analyses with adjustment for enrollment area, knowing that such adjustment limited the exposure contrasts evaluated in the analyses.
Two treatment variables were evaluated in the analyses: the number of days in treatment and the type of admission to the hospital: voluntary or compulsory.
The result of the imputation was 1783 variants that passed quality control (information measure >0.5; average maximum posterior genotype call probability >0.9) measures, totaling 4703 variants evaluated in the analyses of 15q25.
To demonstrate causality between the different outcomes evaluated in the analyses and maternal age a great number of putative intermediaries could have been considered such as the use of fertility treatment, fetal size, gestational weight gain, etc, but that was not the purpose of the study.
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Recently, other molecular biomarkers have been evaluate in the analyses of two groups.
Multivariate analyses were performed by applying backwards-elimination logistic regression to all demographic and socioeconomic variables evaluated in the bivariate analyses; parsimonious models were developed, which included only age and those variables associated with a mutually adjusted p value of <0.10.
Only prognostic factors previously identified in the literature were evaluated in the statistical analyses.
The limited number of architectures evaluated in the NN analyses may explain these mixed results.
Interactions between risk factors were also evaluated in the multivariable analyses.
See consort diagram; Figure 2. Two hypotheses were evaluated in the statistical analyses.
cParticipants with non-overlapping survey periods who were evaluated in the regression analyses.
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