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In this longitudinal study of adults >18 yrs with diabetes monitored for up to 9 yrs (mean 4.6±1.7.7 yrs), 435 subjects at high risk (DN family history) and 400 at low risk (diabetes >10 yrs, normoalbuminuria, no DN family history) for DN progression were evaluated for rate of eGFR change using the linear mixed effects model and progression to ESRD.
To examine the hypothesis that DN family history and albuminuria predict early DN progression, we have assembled a longitudinal cohort of diabetic subjects, with relatively preserved baseline GFR, who were evaluated for rate of eGFR change, progression to ESRD, and mortality, after adjusting for relevant covariates.
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CEO of Professional Science Editing for Scientists @ prosciediting.com