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Therefore, the contribution of baseline WBC count to the overall risk calculation could not be evaluated during the external validation exercise.
Here the candidate gene set was used exclusively to produce noise, as the positions of the candidates in the ranking were never evaluated during the cross-validation procedure.
Thus, the revsions were re-evaluated during the pre-validation study without repeating the IFU formative study.
Subsequently, the revised CRI was evaluated in the validation set.
It was evaluated in the validation group in two ways.
These miRNAs were then evaluated in the validation set.
Only precision and bias can be evaluated during pre-study validation, not accuracy.
The proposed model was evaluated using the validation dataset.
However, the models were evaluated not using the validation cohort.
Thus, although MDA might be determined, for example, during OQ test with calibrated source(s) or during PQ with the intended radionuclide, it would make more sense to evaluate it during validation of the specific analytical method.
We used the variants that were successfully captured during the validation experiment to evaluate sensitivity and PPV.
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