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Conversely, the oil-in-water-based adjuvant we evaluated clearly shifted responses towards a type-2 cellular immune response, dominated by IL-5 (and IL-10), results consistent with other studies evaluating oil-in-water-based adjuvants, including MF59™ [26].
Although PChE activity is used to monitor the liver dysfunction and neurotxicity in humans exposed to several toxic chemicals, the enzymatic activity has not yet been evaluated clearly in the population chronically exposed to arsenic.
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It suggests that health providers do not place emphasis on evaluating clearly patients' nutritional status.
However, our strategy of examining white matter under each Brodmann area has the advantage of evaluating clearly adjacent position and extending into areas contiguous with the ventricles.
However, many problems remain to be solved: controlled studies are necessary to evaluate clearly the benefit of this new therapeutic approach, and standardised criteria will be necessary (extension degree of surgical resection, type and dose of anticancer drugs, effect of higher intrapleural temperature, etc).
The determination of chronic toxicity by long-term exposure to low concentrations of 2-ACBs has to be evaluated more clearly to determine if these compounds are safe to human.
The activity of the PK-directed schedule in CLL, compared to that of the previously evaluated schedules, clearly indicted the importance of flavopiridol PK for clinical activity, and associations were in fact observed between PK and clinical outcomes, including response, cytokine release syndrome (CRS) and tumor lysis syndrome (TLS) [17].
In contrast to the barriers the potential facilitations were evaluated more clearly.
Additionally, the role of avian vaccines should be comprehensively evaluated and clearly defined.
The sociodemographic context within which a breastfeeding service is implemented or evaluated is clearly important.
None of the three methods evaluated was clearly indicative for the fatal outcome, although trends could be observed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com