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Effect measure modification was evaluated by including the following interaction terms: place of residence × education, place of residence × occupation, and education × religion.
The interaction of ADIPO and FFA levels with AVF was evaluated by including the AVF*FFAs or AVF*ADIPO interaction terms in the logistic regression models [ 18].
Potential interaction between two variables was evaluated by including the product of the variables in the logistic regression analyses, and the interaction coefficient was tested using Wald χ2 statistics.
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The level of false positive signals was evaluated by including probes on the array corresponding to the entire chloroplast genome (154,478 bp sequence), which lacks histones and therefore H3K9m2.
Face and content validity were established in the pilot study and also evaluated by including two questions in the main study.
Heterogeneity in associations related to child sex or children's fat intakes were evaluated by including interaction terms in the final models and by stratifying the sample according to sex or fat intakes at or above versus below the median value of 35.7% of energy intake.
Analyses were performed separately for zygosity and sex, and potential interactions between the social indicators and zygosity, sex and age, respectively, were evaluated by including interaction terms in the models and using Wald test statistics.
Lastly, effect modification of the association between arsenic and 8-OHdG by polymorphisms in GSTM1, APE1, and hOGG1 was evaluated by including interaction terms in the model above.
Potential interactions between OH and age or gender on cause-specific mortality were evaluated by including interaction terms in the multivariate model.
The compound effect of the AGE-RAGE-system on primary and secondary outcomes was evaluated by including a RAGE-score in the Cox models.
The joint effect of each SNP and arsenic concentration was evaluated by including an interaction term in the regression models which combined genotype (dominant model) and average arsenic concentration measured continuously.
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