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The enzymatic stability of Polybia-MPI and its analogues was evaluated by a modification of the sensitive radial diffusion assay.
The effect of AE on acute topical inflammation was evaluated by a modification of the methods of Tubaro et al [ 19] and Atta and Alkofahi [ 20]. Adult Swiss albino mice (15 25 g) of either sex were divided into three groups of 10 animals.
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Then, the PMF is evaluated by using a modification of Eq. (8) (using the FEP/US approach): (22) Δ g ξ = Δ G m − kT ln δ x − ξ exp − E TARG x − E m x kT E m.
HK coagulant activity was evaluated by our modification of an APTT test assay [ 28, 29], using total kininogen-deficient plasma purchased from George King (Overland Park, KS) [ 19].
At the final follow-up, functional outcome was evaluated using a modification of the clinical grading system developed by d'Aubigné and Postel [10].
The methodological quality of papers was evaluated using a modification of the Newcastle-Ottawa scale.
The pharmacological synergy of UA and OA was evaluated against M. tuberculosis H37Rv by a modification of the MABA assay [ 25].
The histochemical sections were evaluated under an electron microscope and evaluated by a pathologist according to the severity of the hepatic injury as described by El-Beshbishy et al. [ 26] with modifications.
Motor co-ordination (grip muscle strength) was evaluated by a rota-rod device as described by Jones and Roberts [ 49] with slight modification of Muthuraman et al. [ 32].
Virus-specific antibody-secreting cells (ASC) in the lungs and spleens of mice were evaluated at day 4 post-challenge (with 5xLD50 PR8) by a modification of the ELISPOT assay[28].
Effect modification was evaluated by an interaction term and tested by Wald test.
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