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The condition was evaluated as class V.
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Parameters of angiogenesis were evaluated as above.
Pathological response was then evaluated as follows: Class 1: disappearance of all tumour either on macroscopic or microscopic assessment; Class 2: presence of in situ carcinoma; Class 3: presence of invasive carcinoma with stromal alteration, such as sclerosis or fibrosis; Class 4: no or few modifications of the tumoral appearance.
Multivalent iminosugars conjugated with a morpholine moiety and/or designed as prodrugs have been prepared and evaluated as new classes of pharmacological chaperones for the treatment of Gaucher disease.
These conformationally restricted heterobicyclic scaffolds were evaluated as a novel class of HCV inhibitors.
A series of berbamine glycosides was designed, synthesized and evaluated as a new class of antitumor agents.
A library of fifty-seven 2,4-disubstituted quinazoline derivatives were designed, synthesized and evaluated as a novel class of multi-targeting agents to treat Alzheimer's disease (AD).
A series of pyrrolo[2,3-c]azepine derivatives was designed, synthesized, and evaluated as a new class of inhibitors against protein tyrosine phosphatase 1B (PTP1B) in vitro.
Three series of bitobic arylpiperazine-phenyl-hexahydropyrazinoquino- lines analogues were designed, synthesizedand evaluated as a novel class of selective ligands for the dopamine D3 receptor.
Based on decoquinate, a series of decoquinate derivatives was designed, synthesized, evaluated as a new class of antischistosomal agents against S. japonicum adult worms in vitro.
A series of 5-benzylidene(thio barbiturate-β-d-glycosides were designed, synthio barbiturate-β-d-glycosides class of mushroom thio barbiturate-β-d-glycosides
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CEO of Professional Science Editing for Scientists @ prosciediting.com