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To further evaluate the potential involvement of the entire CCCH family in macrophage activation, we used QPCR to assess their dynamic expression changes during LPS-induced macrophage activation.
To evaluate the potential involvement of CaSR in peptone signalling, we tested the effects of NPS2143 and Calhex231, selective Ca2+-sensing receptor antagonists [ 25, 26].
To evaluate the potential involvement of the RRA somatic mutations on the uveal melanoma tumorigenesis, we searched for significantly mutated genes (SMG) and pathways (SMP) that contain the RRA mutations.
Considering that hypoxia regulates HIF-1α-dependent expression of both GPER and VEGF in different model systems, in the present study we aimed to evaluate the potential involvement of GPER in the expression and function of VEGF in CAFs and breast cancer cells.
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Evaluating the potential involvement of wild avifauna in the emergence of highly pathogenic avian influenza H5N1 (hereafter H5N1) requires detailed analyses of temporal and spatial relationships between wild bird movements and disease emergence.
Therefore, using human alveolar macrophages isolated from normal healthy volunteers, we evaluated the potential involvement of intracellular calcium and tyrosine kinases as potential signal transduction pathways.
In this study we evaluated the potential involvement of caveolae/lipid rafts in the modulation of VEGF-induced redox signal transduction in leukemia cells.
In this study, we evaluated the potential involvement of monocytic EPCs in SSc vasculopathy by examining their quantity as well as their angiogenic and vasculogenic properties using the procedure to enrich circulating precursors for monocyte-derived multipotential cells.
In this study, we evaluated the potential involvement of monocytic endothelial progenitor cells (EPCs) in pathogenic processes of SSc vasculopathy, by determining their number and contribution to blood vessel formation through angiogenesis and vasculogenesis.
Although evaluating the potential involvement of these naturally occurring polymorphisms in GAS virulence requires further time and effort, it is worth noting that whole-genome sequencing analysis can lead to the quick generation of research hypothesis bearing on pathogenesis even during the initial analysis of epidemics.
To further evaluate the potential for the involvement of LOX1 Md 1a in autonomous aroma formation in ripe apple fruits, we investigated the determinants of LOX1 Md 1a specificity by site-directed mutagenesis of the MdLOX1a gene and subsequent biochemical analysis of the heterologously expressed mutant proteins.
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