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Finally, by using the background of the Cys-less PrnB transporter, we evaluate the functional importance of amino acids Q219, K245 and F248 of PrnB, which our previous data had suggested to be involved in the mechanism of PrnB-mediated proline uptake.
Structural modeling was used to evaluate the functional importance and drug accessibility of these sites, which narrowed down the number of candidates.
To evaluate the functional importance of measured Hep-1 and Hep-2 levels in various genetic variants of hemochromatosis, serum was collected from wild-type mice (wt), Hfe KO, Tfr2y245x or Hfe/TfR2y245x mouse.
Thus, our results highlight the need to evaluate the functional importance of the EPIYT and ESIYT variants in EPIYA-B.
Moreover, to better evaluate the functional importance of the ARE site at the ER beta promoter level, ChIP assays were performed.
To evaluate the functional importance of the PKR-eIF2 α pathway in amyloidogenic signaling in TD mice, APP processing was assessed by immunoblotting of APP, BACE1 mature form and amyloid oligomers.
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We next evaluated the functional importance of this extracellular survivin protein.
We next evaluated the functional importance of p90RSK in modulating chemotherapy response by silencing p90RSK with siRNA.
Moreover, it is of equal importance to evaluate the functional roles of elevated ALDH1A3, ALDH3A2 and ALDH7A1 isozymes in ovarian cancer.
The present study aims to evaluate the functional connectivity of the Romanian Natura 2000 forest sites for mammals, and to determine the importance of individual forest patches in maintaining landscape connectivity.
The purpose of the test was to evaluate the functional and technical performance of the platform.
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