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To evaluate the functional effects of mediastinal radiotherapy, pulmonary function post-surgery but pre-radiotherapy was investigated and compared to the pulmonary function 1-3 years post-radiotherapy.
The aim of this study was to develop EGFR-targeted immunoliposomes for enhancing the delivery of CLX to cancer cells and to evaluate the functional effects of these liposomes in cancer cell lines.
Thus, the goal of this study was to evaluate the functional effects of the fusion of a CBM belonging to family 6, which exhibits high affinity to xylan, with the GH11 xylanase from Bacillus subtilis, which does not have a CBM in its wild-type form.
We therefore measured PARG enzymatic activity in the nuclear and cytoplasmic cell fractions to evaluate the functional effects of the antisense PARPG PMO treatment.
In this context and as previously described [29], in order to evaluate the functional effects of passive immunization treatment in mice, groups of non-tg and α-syn tg animals were tested in the water maze.
Having shown that JW74 exerts molecular effects on key mediators of the canonical Wnt signaling pathway, we next wanted to evaluate the functional effects of tankyrase inhibition.
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To evaluate the functional effect of siRNA on phagocytosis, we developed a new in vitro assay for antibody-mediated platelet ingestion by THP-1 cells.
Ongoing works are to evaluate the functional effect of these new analogs in vivo, with Pressure-Volume curve device, and to further test their comparative cardioprotective potential during experimental CLP sepsis.
In order to evaluate the functional effect of the candidate Suppressive miRNAs on the aggressive features of melanoma, we cloned and stably over-expressed them in HAG cells to evaluate their effect in-vitro and in-vivo.
In order to evaluate the functional effect of deletions and duplications separately on the entire population, the polymorphic CNVRs were separated into their respective CN classes (Table 2).
To evaluate the functional effect of this new mutation, wild-type (WT) and mutant (Mut) LRP5 proteins were expressed independently either in the Saos-2 human osteosarcoma cell line or in HEK293T cells along with a luciferase reporter construct.
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