And, the computational burden is evaluated in terms of the number of multiplications, additions, and transpositions.
To reduce the computational burden of evaluating Equation 1 many times, we used an adaptive allele-frequency spectrum in which we decomposed the AFS into bins of different sizes, depending on the fraction of SNPs that occupy a particular region of the frequency space.
When more than three doses are evaluated, our proposed designs are still applicable, but the computational burden increases.
An inexpensive low-fidelity inviscid flow solver handles most of the computational burden by providing data to the optimizer by evaluating objective functions and constraint values in the low-fidelity phase.
To ease the computational burden metamodels, or surrogate models, can be used, to quickly evaluate the performances of a wide set of different cores, individually defined by a set of parameters (pellet diameter, fissile height…), in the study space.
When dealing with binary De Bruijn sequences, avoiding the need to exhaustively evaluate the cross-correlation values in a given family may be very important, due to the computational burden associated to the huge cardinality of a set.
Because these models must be evaluated many times during each iteration, as more types of data are acquired (multi-wavelength or multi-modulation frequency), the computational burden of the algorithms quickly becomes a significant bottleneck.
