Sentence examples for evaluate the compound from inspiring English sources
We chose to evaluate the compound from the original Davidson paper, CMPD1 [ 15] with 2 traditional p38 inhibitors: SD-0006 [ 7] and BIRB 796 [ 20].
Second, comparison of the bottom part (C2) and upper part (C1) of grain with white-belly can evaluate the compound effect of embryo and chalkiness.
In the majority of cases, the standard approach is to evaluate the compound as a single agent and then to consider combination approaches with existing licensed cytotoxic drugs.
Genome-wide transcriptomic analysis is an unbiased approach to evaluate the compound mode of action, but it is still unknown whether the analysis could be widely applicable to classify molecularly targeted anticancer agents.
Furthermore, a visualisation of these compounds is offered, which can be used to independently evaluate the compounds.
To evaluate the compounds for their target and the mechanism by which the compound affects JAK enzyme activity, the compounds were tested against JAK family kinases (JAK1, JAK2, JAK3, and Tyk2) with the Caliper microfluidic mobility-shift platform.
To identify environmental chemicals and drugs that might affect mitochondria dysfunction, we used a qHTS approach to evaluate the compounds from the Tox21 10K compound library that potentially reduce the mitochondrial membrane potential (MMP) in human liver carcinoma (HepG2) cells.
To further evaluate the compounds that were identified as potent mGlu5 PAMs (VU0001850, VU0040237, VU0357121, and VU0125936), we determined their ability to potentiate mGlu5 responses to glutamate in two separate calcium mobilization assays.
We first evaluated the compound intrinsic sensitivity of six representative neurotransmitters to determine priority for the optimization process (i.e., ease in ionization and detection in the MALDI-IMS experiment), namely, ACh, GABA, glutamate, dopamine, serotonin, and norepinephrine (Fig. 1).
Pre-coated silica gel TLC plates (E. Merck, F254) were used for evaluating the compounds.
Human dihydroorotate dehydrogenase inhibition assay was used to evaluate the synthesized compounds as potent hDHODH inhibitors.
