Here we discuss how the issue of equivalence has been dealt with in the area of clinical medicine, and suggest an analogous approach for evaluating substantial equivalence for transgenic crops.
Thus, the use of metabolomic techniques as well as other omics tools to survey the wide range of metabolites is important to evaluate the substantial equivalence of GM crops [7, 12, 19].
Here we present these tolerance intervals for corn, cotton, and soybean, and discuss the merits of using these intervals to evaluate the substantial equivalence of transgenic crops compared with conventional crop varieties.
Other studies have examined the impact of pneumococcal adherence on the activation of lung epithelial cells; however this is the first to evaluate a substantial number of patient isolates for binding activity, and the first to examine differences between high- and low-binding S. pneumoniae in the activation of lung epithelial cells.
Using 20 breast tumor samples and adjusted analytical methods, we observed high overall concordance between the three platforms evaluated, despite substantial differences in the platform composition.
Specifically, we suggest how reference intervals should be calculated for evaluating the substantial equivalence of new transgenic crops relative to existing crop varieties that have a history of safe use.
Although this approach has been suggested for evaluating the substantial equivalence of transgenic crops [ 29, 30], the aforementioned pharmaceutical situation is fundamentally different from that of transgenic-crop composition comparisons.
Therefore, we analysed the Internet by evaluating a substantial number of breast cancer web sites in English and German language, representing the most and second-most frequent language (52.0 and 7.0%, respectively) used on the Internet (Pimienta et al, 2001).
Making use of comparative analyses of fruit quality, tree morphology and phenology conducted over several years, the present work evaluates the substantial equivalence of field-grown transgenic citrus plants relative to their non-GM counterparts.
PET/CT, mostly performed with contrast-enhancement, were independently evaluated with substantial agreement by two readers blinded to any clinical, laboratory or pathology data accumulated after the date of PET/CT.
